Zhu MMT, Shenasa E, Nielsen TO. Sarcomas: immune biomarker expression and checkpoint inhibitor trials. Most cancers Deal with Rev. 2020;91:102115.
Molina ER, Chim LK, Barrios S, Ludwig JA, Mikos AG. Modeling the tumor microenvironment and pathogenic signaling in bone sarcoma. Tissue Eng Half B Rev. 2020;26:249–71.
Gronchi A, Miah AB, Dei Tos AP, Abecassis N, Bajpai J, Bauer S, et al. Smooth tissue and visceral sarcomas: ESMO-EURACAN-GENTURIS medical observe tips for analysis, remedy and follow-up. Ann Oncol. 2021;32:1348–65.
Strauss SJ, Frezza AM, Abecassis N, Bajpai J, Bauer S, Biagini R, et al. Bone sarcomas: ESMO-EURACAN-GENTURIS-ERN PaedCan Scientific Observe Guideline for analysis, remedy and follow-up. Ann Oncol. 2021;32:1520–36.
Lu C, Rong D, Zhang B, Zheng W, Wang X, Chen Z, et al. Present views on the immunosuppressive tumor microenvironment in hepatocellular carcinoma: challenges and alternatives. Mol Most cancers. 2019;18:130.
Kasprzak A. The position of tumor microenvironment cells in colorectal most cancers (CRC) Cachexia. Int J Mol Sci. 2021;22:1565.
Farajzadeh VS, Keshavarz-Fathi M, Silvestris N, Argentiero A, Rezaei N. The position of inflammatory cytokines and tumor related macrophages (TAMs) in microenvironment of pancreatic most cancers. Cytokine Progress Issue Rev. 2018;39:46–61.
Nascimento C, Ferreira F. Tumor microenvironment of human breast most cancers, and feline mammary carcinoma as a possible research mannequin. Biochim Biophys Acta Rev Most cancers. 2021;1876:188587.
Li M, Liu L, Dong M. Progress on pivotal position and software of exosome in lung most cancers carcinogenesis, analysis, remedy and prognosis. Mol Most cancers. 2021;20:22.
Ye H, He X, Feng X. Growing neobavaisoflavone nanoemulsion suppresses lung most cancers development by regulating tumor microenvironment. Biomed Pharmacother. 2020;129:110369.
Berger-Achituv S, Brinkmann V, Abed UA, Kuhn LI, Ben-Ezra J, Elhasid R, et al. A proposed position for neutrophil extracellular traps in most cancers immunoediting. Entrance Immunol. 2013;4:48.
Mcewen A, Emmanuel C, Medbury H, Leick A, Walker DM, Zoellner H. Induction of contact-dependent endothelial apoptosis by osteosarcoma cells suggests a job for endothelial cell apoptosis in blood-borne metastasis. J Pathol. 2003;201:395–403.
Curino A, Mitola DJ, Aaronson H, Mcmahon GA, Raja Ok, Keegan AD, et al. Plasminogen promotes sarcoma development and suppresses the buildup of tumor-infiltrating macrophages. Oncogene. 2002;21:8830–42.
Zhong L, Liao D, Li J, Liu W, Wang J, Zeng C, et al. Rab22a-NeoF1 fusion protein promotes osteosarcoma lung metastasis via its secretion into exosomes. Sign Transduct Goal Ther. 2021;6:59.
Jablonska J, Wu CF, Andzinski L, Leschner S, Weiss S. CXCR2-mediated tumor-associated neutrophil recruitment is regulated by IFN-β. Int J Most cancers. 2014;134:1346–58.
Li J, Zhao C, Li Y, Wen J, Wang S, Wang D, et al. Osteosarcoma exocytosis of soluble LGALS3BP mediates macrophages towards a tumoricidal phenotype. Most cancers Lett. 2022;528:1–15.
Liang X, Guo W, Ren T, Huang Y, Solar Ok, Zhang H, et al. Macrophages cut back the sensitivity of osteosarcoma to neoadjuvant chemotherapy medicine by secreting Interleukin-1 beta. Most cancers Lett. 2020;480:4–14.
Mashouri L, Yousefi H, Aref AR, Ahadi AM, Molaei F, Alahari SK. Exosomes: composition, biogenesis, and mechanisms in most cancers metastasis and drug resistance. Mol Most cancers. 2019;18:75.
Zhang Y, Bi J, Huang J, Tang Y, Du S, Li P. Exosome: a evaluate of its classification, isolation strategies, storage, diagnostic and focused remedy functions. Int J Nanomed. 2020;15:6917–34.
Min L, Shen J, Tu C, Hornicek F, Duan Z. The roles and implications of exosomes in sarcoma. Most cancers Metastasis Rev. 2016;35:377–90.
Huotari J, Helenius A. Endosome maturation. EMBO J. 2011;30:3481–500.
Juan T, Furthauer M. Biogenesis and performance of ESCRT-dependent extracellular vesicles. Semin Cell Dev Biol. 2018;74:66–77.
Wei D, Zhan W, Gao Y, Huang L, Gong R, Wang W, et al. RAB31 marks and controls an ESCRT-independent exosome pathway. Cell Res. 2021;31:157–77.
Fei X, Li Z, Yang D, Kong X, Lu X, Shen Y, et al. Neddylation of Coro1a determines the destiny of multivesicular our bodies and biogenesis of extracellular vesicles. J Extracell Vesicles. 2021;10:e12153.
Ostrowski M, Carmo NB, Krumeich S, Fanget I, Raposo G, Savina A, et al. Rab27a and Rab27b management totally different steps of the exosome secretion pathway. Nat Cell Biol. 2010;12(19–30):1–13.
Tian T, Zhu YL, Zhou YY, Liang GF, Wang YY, Hu FH, et al. Exosome uptake via clathrin-mediated endocytosis and macropinocytosis and mediating miR-21 supply. J Biol Chem. 2014;289:22258–67.
Parolini I, Federici C, Raggi C, Lugini L, Palleschi S, De Milito A, et al. Microenvironmental pH is a key issue for exosome site visitors in tumor cells. J Biol Chem. 2009;284:34211–22.
Kling MJ, Chaturvedi NK, Kesherwani V, Coulter DW, Mcguire TR, Sharp JG, et al. Exosomes secreted below hypoxia improve stemness in Ewing’s sarcoma via miR-210 supply. Oncotarget. 2020;11:3633–45.
Liang M, Chen X, Wang L, Qin L, Wang H, Solar Z, et al. Most cancers-derived exosomal TRIM59 regulates macrophage NLRP3 inflammasome activation to advertise lung most cancers development. J Exp Clin Most cancers Res. 2020;39:176.
Chen J, Zhang Ok, Zhi Y, Wu Y, Chen B, Bai J, et al. Tumor-derived exosomal miR-19b-3p facilitates M2 macrophage polarization and exosomal LINC00273 secretion to advertise lung adenocarcinoma metastasis through Hippo pathway. Clin Transl Med. 2021;11:e478.
Liu G, Ouyang X, Solar Y, Xiao Y, You B, Gao Y, et al. The miR-92a-2-5p in exosomes from macrophages will increase liver most cancers cells invasion through altering the AR/PHLPP/p-AKT/β-catenin signaling. Cell Demise Differ. 2020;27:3258–72.
Dong L, Pu Y, Zhang L, Qi Q, Xu L, Li W, et al. Human umbilical twine mesenchymal stem cell-derived extracellular vesicles promote lung adenocarcinoma development by transferring miR-410. Cell Demise Dis. 2018;9:218.
Jia Y, Ding X, Zhou L, Zhang L, Yang X. Mesenchymal stem cells-derived exosomal microRNA-139-5p restrains tumorigenesis in bladder most cancers by focusing on PRC1. Oncogene. 2021;40:246–61.
Mao Y, Wang Y, Dong L, Zhang Y, Zhang Y, Wang C, et al. Hypoxic exosomes facilitate angiogenesis and metastasis in esophageal squamous cell carcinoma via altering the phenotype and transcriptome of endothelial cells. J Exp Clin Most cancers Res. 2019;38:389.
Shan G, Gu J, Zhou D, Li L, Cheng W, Wang Y, et al. Most cancers-associated fibroblast-secreted exosomal miR-423-5p promotes chemotherapy resistance in prostate most cancers by focusing on GREM2 via the TGF-β signaling pathway. Exp Mol Med. 2020;52:1809–22.
Yu W, Hurley J, Roberts D, Chakrabortty SK, Enderle D, Noerholm M, et al. Exosome-based liquid biopsies in most cancers: alternatives and challenges. Ann Oncol. 2021;32:466–77.
Yang M, Li J, Gu P, Fan X. The applying of nanoparticles in most cancers immunotherapy: focusing on tumor microenvironment. Bioact Mater. 2021;6:1973–87.
Zhou L, Wang W, Wang F, Yang S, Hu J, Lu B, et al. Plasma-derived exosomal miR-15a-5p as a promising diagnostic biomarker for early detection of endometrial carcinoma. Mol Most cancers. 2021;20:57.
Nie H, Xie X, Zhang D, Zhou Y, Li B, Li F, et al. Use of lung-specific exosomes for miRNA-126 supply in non-small cell lung most cancers. Nanoscale. 2020;12:877–87.
Cheng Z, Wang L, Wu C, Huang L, Ruan Y, Xue W. Tumor-derived exosomes induced M2 macrophage polarization and promoted the metastasis of osteosarcoma cells via Tim-3. Arch Med Res. 2021;52:200–10.
Casadei L, Calore F, Creighton CJ, Guescini M, Batte Ok, Iwenofu OH, et al. Exosome-derived miR-25-3p and miR-92a-3p stimulate liposarcoma development. Most cancers Res. 2017;77:3846–56.
Raimondi L, De Luca A, Gallo A, Costa V, Russelli G, Cuscino N, et al. Osteosarcoma cell-derived exosomes have an effect on tumor microenvironment by particular packaging of microRNAs. Carcinogenesis. 2020;41:666–77.
Ucci A, Cappariello A, Ponzetti M, Tennant F, Loftus AEP, Shefferd Ok, et al. Anti-osteoblastogenic, pro-inflammatory and pro-angiogenic impact of extracellular vesicles remoted from the human osteosarcoma cell line MNNG/HOS. Bone. 2021;153:116130.
Garimella R, Washington L, Isaacson J, Vallejo J, Spence M, Tawfik O, et al. Extracellular membrane vesicles derived from 143B osteosarcoma cells comprise pro-osteoclastogenic cargo: a novel communication mechanism in osteosarcoma bone microenvironment. Transl Oncol. 2014;7:331–40.
Lin L, Wang H, Guo W, He E, Huang Ok, Zhao Q. Osteosarcoma-derived exosomal miR-501-3p promotes osteoclastogenesis and aggravates bone loss. Cell Sign. 2021;82:109935.
Araki Y, Aiba H, Yoshida T, Yamamoto N, Hayashi Ok, Takeuchi A, et al. Osteosarcoma-derived small extracellular vesicles improve tumor metastasis and suppress osteoclastogenesis by miR-146a-5p. Entrance Oncol. 2021;11:667109.
Park JE, Dutta B, Tse SW, Gupta N, Tan CF, Low JK, et al. Hypoxia-induced tumor exosomes promote M2-like macrophage polarization of infiltrating myeloid cells and microRNA-mediated metabolic shift. Oncogene. 2019;38:5158–73.
Yakupova EI, Maleev GV, Krivtsov AV, Plotnikov EY. Macrophage polarization in hypoxia and ischemia/reperfusion: insights into the position of energetic metabolism. Exp Biol Med. 2022;247:958–71.
Luong N, Lenz JA, Modiano JF, Olson JK. Extracellular vesicles secreted by tumor cells promote the era of suppressive monocytes. ImmunoHorizons. 2021;5:647–58.
Wolf-Dennen Ok, Gordon N, Kleinerman ES. Exosomal communication by metastatic osteosarcoma cells modulates alveolar macrophages to an M2 tumor-promoting phenotype and inhibits tumoricidal features. Oncoimmunology. 2020;9:1747677.
Lee Ok, An J, Yang S, Park S, Lee J, Chae H, et al. Affect of canine macrophage-derived extracellular vesicles on apoptosis in canine melanoma and osteosarcoma cell traces. Anticancer Res. 2021;41:719–30.
Liu W, Lengthy Q, Zhang W, Zeng D, Hu B, Liu S, et al. miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the expansion and metastasis of osteosarcoma via SOCS3/JAK2/STAT3 axis. Getting old. 2021;13:19760–75.
Zhang H, Yu Y, Wang J, Han Y, Ren T, Huang Y, et al. Macrophages-derived exosomal lncRNA LIFR-AS1 promotes osteosarcoma cell development through miR-29a/NFIA axis. Most cancers Cell Int. 2021;21:192.
Xiong J, Wu L, Huang L, Wu C, Liu Z, Deng W, et al. LncRNA FOXP4-AS1 promotes development of ewing sarcoma and is related to immune infiltrates. Entrance Oncol. 2021;11:718876.
Gassmann H, Schneider Ok, Evdokimova V, Ruzanov P, Schober SJ, Xue B, et al. Ewing sarcoma-derived extracellular vesicles impair dendritic cell maturation and performance. Cells-Basel. 2021;10:2081.
Mazumdar A, Urdinez J, Boro A, Arlt MJE, Egli FE, Niederöst B, et al. Exploring the position of osteosarcoma-derived extracellular vesicles in pre-metastatic area of interest formation and metastasis within the 143-B xenograft mouse osteosarcoma mannequin. Cancers. 2020;12:3457.
Cortini M, Avnet S, Baldini N. Mesenchymal stroma: position in osteosarcoma development. Most cancers Lett. 2017;405:90–9.
Lagerweij T, Pérez-Lanzón M, Baglio SR. A preclinical mouse mannequin of osteosarcoma to outline the extracellular vesicle-mediated communication between tumor and mesenchymal stem cells. J Vis Exp. 2018;135:e56932.
Mannerström B, Kornilov R, Abu-Shahba AG, Chowdhury IM, Sinha S, Seppänen-Kaijansinkko R, et al. Epigenetic alterations in mesenchymal stem cells by osteosarcoma-derived extracellular vesicles. Epigenetics-Us. 2019;14:352–64.
Vallabhaneni KC, Hassler M, Abraham A, Whitt J, Mo Y, Atfi A, et al. Mesenchymal stem/stromal cells below stress enhance osteosarcoma migration and apoptosis resistance through extracellular vesicle mediated communication. PLoS ONE. 2016;11:e166027.
Qi J, Zhang R, Wang Y. Exosomal miR-21-5p derived from bone marrow mesenchymal stem cells promote osteosarcoma cell proliferation and invasion by focusing on PIK3R1. J Cell Mol Med. 2021;25:11016–30.
Wang Y, Chu Y, Li Ok, Zhang G, Guo Z, Wu X, et al. Exosomes secreted by adipose-derived mesenchymal stem cells foster metastasis and osteosarcoma proliferation by rising COLGALT2 expression. Entrance Cell Dev Biol. 2020;8:253.
Qi J, Zhou Y, Jiao Z, Wang X, Zhao Y, Li Y, et al. Exosomes derived from human bone marrow mesenchymal stem cells promote tumor development via hedgehog signaling pathway. Cell Physiol Biochem. 2017;42:2242–54.
Qin F, Tang H, Zhang Y, Zhang Z, Huang P, Zhu J. Bone marrow-derived mesenchymal stem cell-derived exosomal microRNA-208a promotes osteosarcoma cell proliferation, migration, and invasion. J Cell Physiol. 2020;235:4734–45.
Yang Y, Nguyen PNN, Ma H, Ho W, Chen Y, Chien Y, et al. Tumor mesenchymal stromal cells regulate cell migration of atypical teratoid rhabdoid tumor via exosome-mediated miR155/SMARCA4 pathway. Cancers. 2019;11:720.
Zhao W, Qin P, Zhang D, Cui X, Gao J, Yu Z, et al. Lengthy non-coding RNA PVT1 encapsulated in bone marrow mesenchymal stem cell-derived exosomes promotes osteosarcoma development and metastasis by stabilizing ERG and sponging miR-183–5p. Getting old (Albany, NY). 2019;11:9581–96.
Morita T, Fujiwara T, Yoshida A, Uotani Ok, Kiyono M, Yokoo S, et al. Scientific relevance and practical significance of cell-free microRNA-1260b expression profiles in infiltrative myxofibrosarcoma. Sci Rep-Uk. 2020;10:9414.
Urciuoli E, Giorda E, Scarsella M, Petrini S, Peruzzi B. Osteosarcoma-derived extracellular vesicles induce a tumor-like phenotype in regular recipient cells. J Cell Physiol. 2018;233:6158–72.
Endo-Munoz L, Cai N, Cumming A, Macklin R, Merida De Lengthy L, Topkas E, et al. Development of osteosarcoma from a non-metastatic to a metastatic phenotype is causally related to activation of an autocrine and paracrine uPA axis. PLoS ONE. 2015;10:e133592.
Mazumdar A, Urdinez J, Boro A, Migliavacca J, Arlt MJE, Muff R, et al. Osteosarcoma-derived extracellular vesicles induce lung fibroblast reprogramming. Int J Mol Sci. 2020;21:5451.
Zhao A, Zhao Z, Liu W, Cui X, Wang N, Wang Y, et al. Carcinoma-associated fibroblasts promote the proliferation and metastasis of osteosarcoma by transferring exosomal LncRNA SNHG17. Am J Transl Res. 2021;13:10094–111.
Meng W, Hao Y, He C, Li L, Zhu G. Exosome-orchestrated hypoxic tumor microenvironment. Mol Most cancers. 2019;18:57.
Tao SC, Huang JY, Wei ZY, Li ZX, Guo SC. EWSAT1 acts in live performance with exosomes in osteosarcoma development and tumor-induced angiogenesis: the “double stacking impact.” Adv Biosyst. 2020;4:2000152.
Colletti M, Paolini A, Galardi A, Paolo VD, Pascucci L, Russo I, et al. Expression profiles of exosomal miRNAs remoted from plasma of sufferers with desmoplastic small spherical cell tumor. Epigenomics-Uk. 2019;11:489–500.
Avnet S, Lemma S, Cortini M, Di Pompo G, Perut F, Lipreri MV, et al. The discharge of inflammatory mediators from acid-stimulated mesenchymal stromal cells favours tumour invasiveness and metastasis in osteosarcoma. Cancers. 2021;13:5855.
Fujiwara T, Uotani Ok, Yoshida A, Morita T, Nezu Y, Kobayashi E, et al. Scientific significance of circulating miR-25-3p as a novel diagnostic and prognostic biomarker in osteosarcoma. Oncotarget. 2017;8:33375–92.
Ye Z, Zheng Z, Peng L. MicroRNA profiling of serum exosomes in sufferers with osteosarcoma by high-throughput sequencing. J Make investments Med. 2020;68:893–901.
Cuscino N, Raimondi L, De Luca A, Carcione C, Russelli G, Conti L, et al. Gathering novel circulating exosomal microRNA in osteosarcoma cell traces and attainable implications for the illness. Cancers (Basel). 2019;11:1924.
Kohama I, Asano N, Matsuzaki J, Yamamoto Y, Yamamoto T, Takahashi RU, et al. Complete serum and tissue microRNA profiling in dedifferentiated liposarcoma. Oncol Lett. 2021;22:623.
Uotani Ok, Fujiwara T, Yoshida A, Iwata S, Morita T, Kiyono M, et al. Circulating microRNA-92b-3p as a novel biomarker for monitoring of synovial sarcoma. Sci Rep. 2017;7:14634.
Yamaoka B, Nagasaki-Maeoka E, Uekusa S, Hidaka A, Hijikata Ok, Kato R, et al. Exosomal miR-214-3p as a possible novel biomarker for rhabdoid tumor of the kidney. Pediatr Surg Int. 2021;37:1783–90.
Jerez S, Araya H, Thaler R, Charlesworth MC, López-Solís R, Kalergis AM, et al. Proteomic evaluation of exosomes and exosome-free conditioned media from human osteosarcoma cell traces reveals secretion of proteins associated to tumor development. J Cell Biochem. 2017;118:351–60.
Brady JV, Troyer RM, Ramsey SA, Leeper H, Yang L, Maier CS, et al. A preliminary proteomic investigation of circulating exosomes and discovery of biomarkers related to the development of osteosarcoma in a medical mannequin of spontaneous illness. Transl Oncol. 2018;11:1137–46.
Samuel G, Crow J, Klein JB, Service provider ML, Nissen E, Koestler DC, et al. Ewing sarcoma household of tumors-derived small extracellular vesicle proteomics determine potential medical biomarkers. Oncotarget. 2020;11:2995–3012.
Atay S, Wilkey DW, Milhem M, Service provider M, Godwin AK. Insights into the proteome of gastrointestinal stromal tumors-derived exosomes reveals new potential diagnostic biomarkers. Mol Cell Proteomics. 2018;17:495–515.
Wang J, Zhang H, Solar X, Wang X, Ren T, Huang Y, et al. Exosomal PD-L1 and N-cadherin predict pulmonary metastasis development for osteosarcoma sufferers. J Nanobiotechnol. 2020;18:151.
Han Z, Peng C, Yi J, Wang Y, Liu Q, Yang Y, et al. Matrix-assisted laser desorption ionization mass spectrometry profiling of plasma exosomes evaluates osteosarcoma metastasis. iScience. 2021;24:102906.
Han Z, Yi J, Yang Y, Li D, Peng C, Lengthy S, et al. SERS and MALDI-TOF MS based mostly plasma exosome profiling for fast detection of osteosarcoma. Analyst. 2021;146:6496–505.
Stegmaier S, Sparber-Sauer M, Aakcha-Rudel E, Munch P, Reeh T, Feuchtgruber S, et al. Fusion transcripts as liquid biopsy markers in alveolar rhabdomyosarcoma and synovial sarcoma: a report of the Cooperative Weichteilsarkom Studiengruppe (CWS). Pediatr Blood Most cancers. 2022;69:e29652.
Zhang H, Wang J, Ren T, Huang Y, Yu Y, Chen C, et al. LncRNA CASC15 is upregulated in osteosarcoma plasma exosomes and CASC15 knockdown inhibits osteosarcoma development by regulating miR-338-3p/RAB14 axis. Onco Targets Ther. 2020;13:12055–66.
Pan Y, Lin Y, Mi C. Cisplatin-resistant osteosarcoma cell-derived exosomes confer cisplatin resistance to recipient cells in an exosomal circ_103801-dependent method. Cell Biol Int. 2021;45:858–68.
Wang L, Wu J, Track S, Chen H, Hu Y, Xu B, et al. Plasma exosome-derived sentrin SUMO-specific protease 1: a prognostic biomarker in sufferers with osteosarcoma. Entrance Oncol. 2021;11:625109.
Yoshida A, Fujiwara T, Uotani Ok, Morita T, Kiyono M, Yokoo S, et al. Scientific and practical significance of intracellular and extracellular microRNA-25-3p in osteosarcoma. Acta Med Okayama. 2018;72:165–74.
Weinman MA, Ramsey SA, Leeper HJ, Brady JV, Schlueter A, Stanisheuski S, et al. Exosomal proteomic signatures correlate with drug resistance and carboplatin remedy consequence in a spontaneous mannequin of canine osteosarcoma. Most cancers Cell Int. 2021;21:245.
Hu X, Wen Y, Tan LY, Wang J, Tang F, Wang YT, et al. Exosomal lengthy non-coding RNA ANCR mediates drug resistance in osteosarcoma. Entrance Oncol. 2021;11:735254.
Torreggiani E, Roncuzzi L, Perut F, Zini N, Baldini N. Multimodal switch of MDR by exosomes in human osteosarcoma. Int J Oncol. 2016;49:189–96.
Shiozawa Ok, Shuting J, Yoshioka Y, Ochiya T, Kondo T. Extracellular vesicle-encapsulated microRNA-761 enhances pazopanib resistance in synovial sarcoma. Biochem Biophys Res Commun. 2018;495:1322–7.
Wei H, Chen J, Wang S, Fu F, Zhu X, Wu C, et al. A nanodrug consisting of doxorubicin and exosome derived from mesenchymal stem cells for osteosarcoma remedy in vitro. Int J Nanomed. 2019;14:8603–10.
Shimbo Ok, Miyaki S, Ishitobi H, Kato Y, Kubo T, Shimose S, et al. Exosome-formed artificial microRNA-143 is transferred to osteosarcoma cells and inhibits their migration. Biochem Biophys Res Commun. 2014;445:381–7.
Huang X, Wu W, Jing D, Yang L, Guo H, Wang L, et al. Engineered exosome as focused lncRNA MEG3 supply autos for osteosarcoma remedy. J Management Launch. 2022;343:107–17.
Behzadi E, Hosseini HM, Halabian R, Fooladi A. Macrophage cell-derived exosomes/staphylococcal enterotoxin B towards fibrosarcoma tumor. Microb Pathog. 2017;111:132–8.
Smyth T, Kullberg M, Malik N, Smith-Jones P, Graner MW, Anchordoquy TJ. Biodistribution and supply effectivity of unmodified tumor-derived exosomes. J Management Launch. 2015;199:145–55.
Takahashi Y, Nishikawa M, Shinotsuka H, Matsui Y, Ohara S, Imai T, et al. Visualization and in vivo monitoring of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection. J Biotechnol. 2013;165:77–84.
Yang Z, Shi J, Xie J, Wang Y, Solar J, Liu T, et al. Massive-scale era of practical mRNA-encapsulating exosomes through mobile nanoporation. Nat Biomed Eng. 2020;4:69–83.
Parada N, Romero-Trujillo A, Georges N, Alcayaga-Miranda F. Camouflage methods for therapeutic exosomes evasion from phagocytosis. J Adv Res. 2021;31:61–74.
Thery C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, et al. Minimal data for research of extracellular vesicles 2018 (MISEV2018): a place assertion of the Worldwide Society for Extracellular Vesicles and replace of the MISEV2014 tips. J Extracell Vesicles. 2018;7:1535750.
Chen YS, Lin EY, Chiou TW, Harn HJ. Exosomes in medical trial and their manufacturing in compliance with good manufacturing observe. Ci Ji Yi Xue Za Zhi. 2020;32:113–20.
Zhang Ok, Dong C, Chen M, Yang T, Wang X, Gao Y, et al. Extracellular vesicle-mediated supply of miR-101 inhibits lung metastasis in osteosarcoma. Theranostics. 2020;10:411–25.
Xue Q, Yang Y, Yang L, Yan X, Shen Z, Liu J, et al. miR-371b-5p-engineered exosomes enhances tumor inhibitory impact. Entrance Cell Dev Biol. 2021;9:750171.